Hi scotty i have an 04 chevy silverado 2500HD 6.0l v8 gas automatic with 289k i have an issue with this p0300 no other code's show up

i changed spark plug's and wire's , ignition coil's 8, cleaned injector's , maf sensor cleaned , vaccum 15- 16 in-hg at idle no fluctation, . I recently purchased a Bi-directional scan tool THINKDIAG to see which cylinder is misfiring and found out to be cyl 1 & 6 are the misfire's cyl 6 has the highest number and i need help i wrote down the data sheet freeze frame.

ENGINE COOLANT TEMPERTURE : 201.2 F

ENGINE LOAD : 16.80%

ENGINE SPEED : 2449.75RPM

LONG TERM FUEL TRIM BANK 1 : 10.16%

LONG TERM FUEL TRIM BAKK 2 : 11.72%

LOOP STATUS : CLOSED

MANIFOLD ABSOLUTE PRESSURE MAP SENSOR : 7.25 PSI

MANIFOLD ABSOLUTE PRESSURE MAP SENSOR : 2.12 V

MASS AIR FLOW MAF SENSOR : 47.60 G/S

POWERTRAIN INDUCED CHASSIS PITCH COMMAND : INACTIVE

SHORT TERM FUEL TRIM BANK 1 : 4.69%

SHORT TERM FUEL TRIM BANK 2 : 3.12%

TORQUE CONVERTER CLUTCH TCC PWM SOLENOID COMMAND : OFF

TORQUE CONVERTER CLUTCH TCC/CC BRAKE SWITCH : RELEASED

TRACTION CONTROL : INACTIVE

VEHICLE SPEED SENSOR : 64.63 MPH