If you just want 100k miles out of the vehicle, it doesn't matter if it is a Hybrid or classic ICE. You'll be fine for that long.

Longer term owners have to consider the downsides of battery replacement, etc.

The latest generation of Honda Hybrids are different than previous generation Honda Hybrids and current generations Toyota Hybrids.  The Honda Hybrid acts more like an EV with a gas generator rather than a traditional hybrid.

In usual hybrids like the Prius Hybrid and Toyota technology, the ICE (Internal Combustion Engine) and the electric motor go back and forth, throughout most speed ranges.  The ICE actually drives the car.

With the Honda Hybrid and Insight, the electric motor drives the car until about 45 MPH, and then the ICE may take over. The ICE acts more like a generator than actually drive the car below 45 MPH.  So you basically have an gas powered EV, similar to a hydrogen powered EV, for anything below 45 MPH.

One of the biggest benefits of the latest Honda Hybrid technology, is that when the engine does run, it is operating at near peak efficiency and rev range when compared to regular cars and even Toyota Hybrids.

It's compelling technology, but not as time tested as Toyota Hybrid technology.  Honda is a company that focuses on quality, so I would be open to an Honda Hybrid.  I know other on the forum like to see how things pan out the first few years of a model before jumping on board.

If you want tried and true, the hybrid technology in the Toyota has been battle tested for almost 20 years. 

If you are willing to take a chance on compelling new hybrid technology (practically an electronic vehicle) from a trusted company, go Insight. I am a little more adventurous, so I would probably go Insight (and I currently have a Gen 2 Prius.)

With that said if you were going to get a Hybrid, the only two companies I would get them from is Honda and Toyota.