A local dealer has both of these vehicles on their lot.  Though two very different vehicles, both would suit my needs. 

I'm going to be taking a job later this year that will involve a fairly long daily commute (about 50 miles each way) in a snow state.  So reliability and AWD capability are high on the list.  I also want a bit of sportiness and a little luxury at this point in my life.

The Lexus currently has 108k miles with 1 owner, and the Acura has 87k with 2 owners.   Both have AWD, both have a 3.5L V-6 mated to an automatic transmission.  The asking price for the Lexus is a little higher than the Acura, but its a small difference and both are within my budget.

I'm leaning towards the Lexus because I'm historically more of a car guy. I also like that it has a timing chain rather than a belt and, IMHO, Toyota makes a little bit better automatic transmission than Honda.

OTOH, I do prefer the looks of the MDX, and the extra cargo space would be handy when I go camping and need to haul stuff around. 

Obviously, I'm going to get a pre-purchase inspection before I buy either one.  But anyone have experience with either vehicle?

TIA.