Nissan
Clarification: Can you provide more details - which engine, what is mileage? What symptoms is the car exhibiting besides throwing that code? Are there other codes?
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That shows an imbalance in the number four cylinder meaning there's a problem in that aspect of the vehicle. It could be a fuel injector problem on that a vacuum leak somewhere a blowing head gasket on that cylinder or some other problem. I would begin by doing a wet and dry compression test to see if that's cylinder was physically worn
