Scotty I agree with you about RFT tires however my Toyota Sienna only comes with them so there is no choice.
You do realise you have the option of swapping them to regular tubeless tyres, yes?
As long as you keep the specs the same as stock, there’s no problem.
yup. I would also carry tire plugs and an AAA membership.
Add a tyre inflator and you’re pretty much all set, unless you have a cut in the sidewall or something which instantly ruins the tyre.
yes you can! Your car will probably ride better too.
Yes you can. Just need to decide on a contingency to deal with a flat tire situation. Get a spare tire or small compressor and a can of fix-a-flat, etc. AAA is a good idea too.
Commonly done on cars in the 1960s that came with run-flat tires, like 3-seat Rambler station wagons where there was no room for a spare tire. I don't think anyone ever bothered installing new run-flats once the originals needed to be replaced. As others have mentioned you just need to be equipped for a flat tire situation whether that's going to be AAA (they may takes hours to get to you), carrying repair plugs and a 12V compressor, or just tossing a spare tire in wherever it can fit.
Here's a discussion of which Siennas come with run flats and which come with spare tires, and how to add a spare to a Sienna
https://www.siennachat.com/threads/spare-tire-vs-no-spare-tire.69556/
